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KMID : 0381019700030030161
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Korean Journal of Nutrition
1970 Volume.3 No. 3 p.161 ~ p.166
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Hemoglobin variant Found in Koreans
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Abstract
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One male in the former group of 2110 Korean males of the Republic of` Korea Army stationed Taegu. And two males and one female in the later group of 4590 Korean school children and university students in Seoul and Taejuon were found to have a slow hemoglobin in addition to normal hemoglobin A.
In all four subjects the slow component migrated at a rate characteristic of the G hemoglobin. The overall incidence of the variant in the present group of Koreans was low: 4 in 6700 or 0.06 per cent.
It appears significant that no insitance of hemoglobin E were found among these Korean subjects. Hemoglobin E has been found among numerous ethnic groups of Southeast Asia and the variant most frequently appeared in Chinese subject.
By Urea-Starch-Gel Electrophoresis in Alkaline PH and A.I. Chernoff method was demonstrated that another 3 cases of abnormal hemoglobin also were beta-chain variants. This was reconfed by Hybridization Experiment with canine hemoglobin.
And the results of family test of 3 case of abnormal hemoglobin were heterozygous carrier.
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